The Hope for African Children Initiative (HACI) is an innovative response that addresses the entire child-focused prevention-care-mitigation continuum with mutually reinforcing program strategies.

Wild4Life started as an HIV/AIDS program in Zimbabwe, but has expanded to building rural health systems throughout sub-Saharan African countries. Piloting rural health clinics, monitoring health needs of rural populations and developing local partnerships has dramatically improved health outcomes.

North Star Alliance is a non-profit, public-private partnership that is establishing a network of roadside health clinics at major truck stops and border crossings to serve hard-to-reach populations across Africa.

All HIV services, including antiretroviral therapy, are extended to all mothers' HIV-infected children, partners, and other family members. The initiative is known internationally as a model program for family-based care and the early diagnosis and care of infants exposed and infected with HIV.