The Hope for African Children Initiative (HACI) is an innovative response that addresses the entire child-focused prevention-care-mitigation continuum with mutually reinforcing program strategies.

mothers2mothers uses a Mentor Mother Model to empower mothers living with HIV, through education and employment, as role models to help other women access essential services and medical care.

North Star Alliance is a non-profit, public-private partnership that is establishing a network of roadside health clinics at major truck stops and border crossings to serve hard-to-reach populations across Africa.

All HIV services, including antiretroviral therapy, are extended to all mothers' HIV-infected children, partners, and other family members. The initiative is known internationally as a model program for family-based care and the early diagnosis and care of infants exposed and infected with HIV.